Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Six3  sine oculis-related homeobox 3   (Synonyms: E130112M24Rik)
Results	Reference
1	J:334460 Bando H, Brinkmeier ML, Castinetti F, Fang Q, Lee MS, Saveanu A, Albarel F, Dupuis C, Brue T, Camper SA, Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man. Hum Mol Genet. 2023 Jan 13;32(3):367-385
1	J:271140 Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W, Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Rep. 2018 Nov 27;25(9):2510-2523.e4
1	J:208421 Klimova L, Kozmik Z, Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302
1	J:246467 Liu W, Cvekl A, Six3 in a small population of progenitors at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice. Dev Biol. 2017 Aug 01;428(1):164-175
1	J:165328 Liu W, Lagutin O, Swindell E, Jamrich M, Oliver G, Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate. J Clin Invest. 2010 Oct 1;120(10):3568-77
1	J:116102 Liu W, Lagutin OV, Mende M, Streit A, Oliver G, Six3 activation of Pax6 expression is essential for mammalian lens induction and specification. EMBO J. 2006 Nov 15;25(22):5383-95
1	J:276721 Liu Z, Li C, Xu J, Lan Y, Liu H, Li X, Maire P, Wang X, Jiang R, Crucial and Overlapping Roles of Six1 and Six2 in Craniofacial Development. J Dent Res. 2019 May;98(5):572-579
1*	J:103131 Purcell P, Oliver G, Mardon G, Donner AL, Maas RL, Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction. Gene Expr Patterns. 2005 Dec;6(1):110-8
1	J:250948 Schock EN, Brugmann SA, Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division. Dev Biol. 2017 Nov 15;431(2):168-178
1	J:255241 Takata N, Abbey D, Fiore L, Acosta S, Feng R, Gil HJ, Lavado A, Geng X, Interiano A, Neale G, Eiraku M, Sasai Y, Oliver G, An Eye Organoid Approach Identifies Six3 Suppression of R-spondin 2 as a Critical Step in Mouse Neuroretina Differentiation. Cell Rep. 2017 Nov 7;21(6):1534-1549
1	J:139698 Wataya T, Ando S, Muguruma K, Ikeda H, Watanabe K, Eiraku M, Kawada M, Takahashi J, Hashimoto N, Sasai Y, Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11796-801
1	J:211220 Wolf L, Harrison W, Huang J, Xie Q, Xiao N, Sun J, Kong L, Lachke SA, Kuracha MR, Govindarajan V, Brindle PK, Ashery-Padan R, Beebe DC, Overbeek PA, Cvekl A, Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. Nucleic Acids Res. 2013 Dec;41(22):10199-214
1	J:154982 Yun S, Saijoh Y, Hirokawa KE, Kopinke D, Murtaugh LC, Monuki ES, Levine EM, Lhx2 links the intrinsic and extrinsic factors that control optic cup formation. Development. 2009 Dec;136(23):3895-906